| NCT02375867 |
Steroids in Fulminant Hepatitis A in the Pediatric Age Group |
https://ClinicalTrials.gov/show/NCT02375867 |
Completed |
National Liver Institute, Egypt |
2017-08-31 |
| NCT03940742 |
A Study of Tirzepatide in Participants With Impaired Liver Function |
https://ClinicalTrials.gov/show/NCT03940742 |
Recruiting |
Eli Lilly and Company |
2020-08-18 |
| NCT03878329 |
Telemedicine Based Remote Home Monitoring After Liver Transplantation |
https://ClinicalTrials.gov/show/NCT03878329 |
Active, not recruiting |
University of Cincinnati |
2019-07-01 |
| NCT03341884 |
A Study of Ipatasertib in Participants With Mild, Moderate or Severe Hepatic Impairment Compared to Healthy Participants |
https://ClinicalTrials.gov/show/NCT03341884 |
Completed |
Genentech, Inc. |
2018-06-26 |
| NCT03312036 |
HEpatic Regeneration With COupled Plasma Filtration and Adsorption for Liver Extracorporeal Detoxification |
https://ClinicalTrials.gov/show/NCT03312036 |
Completed |
St. Orsola Hospital |
2018-12-21 |
| NCT03306667 |
Clinical Pharmacology of FYU-981 (Subjects With Hepatic Insufficiency) |
https://ClinicalTrials.gov/show/NCT03306667 |
Completed |
Mochida Pharmaceutical Company, Ltd. |
2018-06-20 |
| NCT03216668 |
TONKA Versus Legalon for Lowering Hepatic Enzymes in Liver Function Disorder Patients. |
https://ClinicalTrials.gov/show/NCT03216668 |
Recruiting |
Nhat Nhat Pharmaceutical Company |
2019-06-30 |
| NCT03172884 |
Study of Copanlisib in Hepatic or Renal Impairment |
https://ClinicalTrials.gov/show/NCT03172884 |
Completed |
Bayer |
2020-03-13 |
| NCT03082885 |
The Efficacy and Safety of Thymosin-α1 in Patients With HBV-related ACLF |
https://ClinicalTrials.gov/show/NCT03082885 |
Completed |
Sun Yat-sen University |
2019-06-02 |
| NCT03044639 |
Parenteral Lipid Emulsions and the Liver Function |
https://ClinicalTrials.gov/show/NCT03044639 |
Completed |
Stanley Dudrick’s Memorial Hospital |
2016-10-31 |
| NCT02946554 |
Phase II Safety Study of 2 Dose Regimens of HepaStem in Patients With ACLF |
https://ClinicalTrials.gov/show/NCT02946554 |
Active, not recruiting |
Promethera Biosciences |
2019-07-31 |
| NCT02894385 |
Effect of Hepatic and Renal Impairment on the Pharmacokinetics, Safety and Tolerability of BAY1841788 (ODM-201) |
https://ClinicalTrials.gov/show/NCT02894385 |
Completed |
Bayer |
2017-04-10 |
| NCT02837939 |
Transfer Factor Efficacy in the Management of Cirrhosis-associated Immune Dysfunction |
https://ClinicalTrials.gov/show/NCT02837939 |
Recruiting |
Pavol Jozef Safarik University |
2020-07-31 |
| NCT02753517 |
Hepato Biliary Scintigraphy to Assess the Risk of Postoperative Liver Failure Hepatectomies |
https://ClinicalTrials.gov/show/NCT02753517 |
Recruiting |
University Hospital, Lille |
2020-11-30 |
| NCT02719210 |
High Volume Plasma Exchange in Children With Acute Liver Failure and Acute on Chronic Liver Failure |
https://ClinicalTrials.gov/show/NCT02719210 |
Completed |
Institute of Liver and Biliary Sciences, India |
2018-11-30 |
| NCT02718079 |
High-Volume Plasma Exchange Versus Standard Medical Treatment in Patients With Acute Liver Failure |
https://ClinicalTrials.gov/show/NCT02718079 |
Completed |
Institute of Liver and Biliary Sciences, India |
2018-10-08 |
| NCT02691533 |
To Study the Immunomodulating Effects and Safety Profile of ω3 and ω6 PUFA Containing Intravenous Lipid Emulsion in Patients With Acute on Chronic Liver Failure |
https://ClinicalTrials.gov/show/NCT02691533 |
Completed |
Institute of Liver and Biliary Sciences, India |
2017-12-31 |
| NCT02689245 |
Randomized Controlled Trial Comparing the Efficacy and Safety of FMT in Hepatitis B Reactivation Leads to Acute on Chronic Liver Failure. |
https://ClinicalTrials.gov/show/NCT02689245 |
Completed |
Institute of Liver and Biliary Sciences, India |
2018-03-13 |
| NCT02687763 |
Safety and Efficacy of ProQuad® in Children 6-24 Month Being Evaluated for Solid Organ Transplant |
https://ClinicalTrials.gov/show/NCT02687763 |
Completed |
Medical University of South Carolina |
2016-11-03 |
| NCT02669680 |
Granulocyte Colony Stimulating Factor (G-CSF) to Treat Acute-on-chronic Liver Failure |
https://ClinicalTrials.gov/show/NCT02669680 |
Active, not recruiting |
University of Leipzig |
2020-03-31 |
| NCT02666352 |
A Study of the Pharmacokinetics of Uprifosbuvir (MK-3682) and Ruzasvir (MK-8408) in Participants With Moderate and Severe Hepatic Insufficiency (MK-3682-029) |
https://ClinicalTrials.gov/show/NCT02666352 |
Completed |
Merck Sharp & Dohme Corp. |
2017-01-16 |
| NCT02635347 |
Remote Ischemic Conditioning (RIC) in Recipients of Brain Death Donor Livers - A Feasibility and Safety Study |
https://ClinicalTrials.gov/show/NCT02635347 |
Completed |
Rutgers, The State University of New Jersey |
2017-10-31 |
| NCT02584283 |
Dual Hypothermic Oxygenated Perfusion of DCD Liver Grafts in Preventing Biliary Complications After Transplantation |
https://ClinicalTrials.gov/show/NCT02584283 |
Completed |
University Medical Center Groningen |
2020-01-31 |
| NCT03065699 |
Safety and Performance Trial of DIALIVE Liver Dialysis Device in Acute On Chronic Liver Failure Patients |
https://ClinicalTrials.gov/show/NCT03065699 |
Active, not recruiting |
Yaqrit Ltd |
2019-12-31 |
| NCT02573727 |
To Compare the Response Rate of Noradrenaline vs. Terlipressin in Hepatorenal Syndrome in Patients With Acute on Chronic Liver Failure |
https://ClinicalTrials.gov/show/NCT02573727 |
Completed |
Institute of Liver and Biliary Sciences, India |
2017-01-31 |
| NCT02786836 |
13C-Methacetin Breath Test for the Prediction of Outcome in in ALI or ALF |
https://ClinicalTrials.gov/show/NCT02786836 |
Completed |
University of Texas Southwestern Medical Center |
2019-09-18 |
| NCT02544113 |
A Randomized Controlled Clinical Trial of Thymoglobulin® After Liver Transplantation |
https://ClinicalTrials.gov/show/NCT02544113 |
Active, not recruiting |
The Cleveland Clinic |
2020-09-30 |
| NCT02467348 |
Incidence And Outcome Of Paracentesis Induced Circulatory Dysfunction In Acute-On-Chronic Liver Failure. |
https://ClinicalTrials.gov/show/NCT02467348 |
Completed |
Institute of Liver and Biliary Sciences, India |
2017-01-31 |
| NCT02460510 |
Role of Hypertonic Saline Versus Mannitol in the Management of Raised Intracranial Pressure in Patients With ALF |
https://ClinicalTrials.gov/show/NCT02460510 |
Completed |
Institute of Liver and Biliary Sciences, India |
2015-11-30 |
| NCT02457702 |
Mitochondrial Function in Patients With Severe Liver Disease |
https://ClinicalTrials.gov/show/NCT02457702 |
Recruiting |
University of Texas Southwestern Medical Center |
2021-12-31 |
| NCT02455115 |
Renal Perfusion, Filtration and Oxygenation After Liver Transplantation -Effects of av Postoperative Blood Pressure |
https://ClinicalTrials.gov/show/NCT02455115 |
Completed |
Sahlgrenska University Hospital, Sweden |
2016-02-29 |
| NCT02390713 |
Pneumatic Reversible Portal Vein Diameter Modulation After Major Hepatectomy |
https://ClinicalTrials.gov/show/NCT02390713 |
Recruiting |
Assistance Publique - Hôpitaux de Paris |
2020-04-30 |
| NCT02387814 |
A Study of Abemaciclib in Participants With Varying Degrees of Liver Impairment |
https://ClinicalTrials.gov/show/NCT02387814 |
Completed |
Eli Lilly and Company |
2015-08-31 |
| NCT02334800 |
A Study To Describe The Effect Of Impaired Hepatic Function Of The Pharmacokinetics Of Palbociclib |
https://ClinicalTrials.gov/show/NCT02334800 |
Completed |
Pfizer |
2016-10-09 |
| NCT02321371 |
Effect of Goal Directed Ammonia Lowering Therapy in Acute on Chronic Liver Failure Patients With Hepatic Encephalopathy. |
https://ClinicalTrials.gov/show/NCT02321371 |
Completed |
Institute of Liver and Biliary Sciences, India |
2016-01-31 |
| NCT02318836 |
Single-Dose Pharmacokinetics and Safety of Oral Lofexidine in Hepatically-Impaired Subjects |
https://ClinicalTrials.gov/show/NCT02318836 |
Completed |
US WorldMeds LLC |
2014-10-31 |
| NCT02310542 |
Comparison of Two Liver Dialysis Systems : MARS Versus SPAD in Severe Liver Failure |
https://ClinicalTrials.gov/show/NCT02310542 |
Completed |
Hospices Civils de Lyon |
2017-09-30 |
| NCT02265627 |
Pharmacokinetics, Safety and Tolerability of BIIL 284 BS in Patients With Hepatic Impairment in Comparison to Healthy Volunteers |
https://ClinicalTrials.gov/show/NCT02265627 |
Completed |
Boehringer Ingelheim |
2000-09-30 |
| NCT02259855 |
Pharmacokinetics (PK) of Tipranavir/Ritonavir, Ribavirin, Pegylated Interferon (Peg INF) in Hepatitis C (HCV) Subjects With Mild Hepatic Impairment and in HCV, Hepatitis B (HBV), Hepatitis D Infected Subjects or Alcoholic Cirrhosis With Moderate Hepatic Impairment |
https://ClinicalTrials.gov/show/NCT02259855 |
Completed |
Boehringer Ingelheim |
2008-10-31 |
| NCT02249442 |
Study to Determine the Pharmacokinetics on TPV/r in Subjects With Mild and Moderate Hepatic Insufficiency |
https://ClinicalTrials.gov/show/NCT02249442 |
Completed |
Boehringer Ingelheim |
2004-06-30 |
| NCT02191865 |
Nintedanib in Volunteers With Hepatic Impairment Compared With Healthy Volunteers |
https://ClinicalTrials.gov/show/NCT02191865 |
Completed |
Boehringer Ingelheim |
2014-12-31 |
| NCT02184091 |
Study to Evaluate the Effects of Underlying Renal or Hepatic Dysfunction on the Pharmacokinetics of Nevirapine |
https://ClinicalTrials.gov/show/NCT02184091 |
Completed |
Boehringer Ingelheim |
1999-07-31 |
| NCT02183376 |
Pharmacokinetics and Pharmacodynamics of BI 1356 in Subjects With Different Degrees of Liver Impairment as Compared to Healthy Subjects |
https://ClinicalTrials.gov/show/NCT02183376 |
Completed |
Boehringer Ingelheim |
2009-03-31 |
| NCT02170571 |
Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Dabigatran Etexilate in Patients With Moderate Hepatic Impairment Compared to Subjects With Normal Hepatic Function |
https://ClinicalTrials.gov/show/NCT02170571 |
Completed |
Boehringer Ingelheim |
2005-12-31 |
| NCT02161224 |
A Study to Investigate the Exposure and Safety and Tolerability of a Single Dose of FG-4592 in Subjects With Moderately Diminished Liver Function Compared to Those With Normal Liver Function |
https://ClinicalTrials.gov/show/NCT02161224 |
Completed |
Astellas Pharma Inc |
2013-12-31 |
| NCT02120547 |
Phase 1 Study of Multiple-Dose Pharmacokinetics of Cenicriviroc in Subjects With Mild and Moderate Hepatic Impairment |
https://ClinicalTrials.gov/show/NCT02120547 |
Completed |
Tobira Therapeutics, Inc. |
2014-07-31 |
| NCT02115321 |
Study of Efficacy and Safety of Grazoprevir (MK-5172) + Elbasvir (MK-8742) in Chronic Hepatitis C Participants With Child-Pugh (CP)-B Hepatic Insufficiency (MK-5172-059) |
https://ClinicalTrials.gov/show/NCT02115321 |
Completed |
Merck Sharp & Dohme Corp. |
2015-03-05 |
| NCT02090621 |
Extracorporeal Photopheresis After Liver Transplant |
https://ClinicalTrials.gov/show/NCT02090621 |
Completed |
Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia |
2013-10-31 |
| NCT02089659 |
A Study to Investigate the Influence of Hepatic Insufficiency on the Pharmacokinetics of Doravirine (MK-1439) (MK-1439-019) |
https://ClinicalTrials.gov/show/NCT02089659 |
Completed |
Merck Sharp & Dohme Corp. |
2014-05-12 |
| NCT01273493 |
A Pharmacokinetic Study of Trabectedin in Patients With Advanced Malignancies and Hepatic Dysfunction |
https://ClinicalTrials.gov/show/NCT01273493 |
Completed |
Janssen Research & Development, LLC |
2014-04-30 |
| NCT01968395 |
Pharmacokinetics of Caspofungin After One Dose in Patients With Liver Failure |
https://ClinicalTrials.gov/show/NCT01968395 |
Completed |
Erasme University Hospital |
2014-08-31 |
| NCT01946360 |
Role of 13C Methacetin Breath Test in Predicting Prognosis Among Patients With Acute or Acute on Chronic Liver Failure (ACLF). |
https://ClinicalTrials.gov/show/NCT01946360 |
Completed |
Institute of Liver and Biliary Sciences, India |
2015-01-31 |
| NCT01916993 |
Safety, Tolerability, and Pharmacokinetics of a Single Dose of NBI-98854 in Subjects With Mild,Moderate, or Severe Hepatic Insufficiency |
https://ClinicalTrials.gov/show/NCT01916993 |
Completed |
Neurocrine Biosciences |
2013-12-31 |
| NCT01870388 |
A Pharmacokinetic Study of Baricitinib in Participants With Liver Disease |
https://ClinicalTrials.gov/show/NCT01870388 |
Completed |
Eli Lilly and Company |
2013-07-31 |
| NCT01860326 |
Evaluate the Pharmacokinetics, Safety, and Tolerability of Alisporivir in Subjects With Hepatic Impairment Compared to Healthy Subjects |
https://ClinicalTrials.gov/show/NCT01860326 |
Completed |
Debiopharm International SA |
2011-09-30 |
| NCT01846455 |
Single Dose Pharmacokinetics of Suboxone Study in Hepatic Impaired Subjects |
https://ClinicalTrials.gov/show/NCT01846455 |
Completed |
Indivior Inc. |
2013-04-30 |
| NCT01836185 |
A Study of Evacetrapib (LY2484595) in Participants With Hepatic (Liver) Impairment |
https://ClinicalTrials.gov/show/NCT01836185 |
Completed |
Eli Lilly and Company |
2013-10-31 |
| NCT01797536 |
The Influence of Hepatic Insufficiency on the Pharmacokinetics of Elbasvir (MK-8742) (MK-8742-009) |
https://ClinicalTrials.gov/show/NCT01797536 |
Completed |
Merck Sharp & Dohme Corp. |
2014-08-20 |
| NCT01785082 |
Fast-track LiveR: Study for the Early Identification of Low-risk Patients After Partial Liver Resection by the LiMAx-test |
https://ClinicalTrials.gov/show/NCT01785082 |
Completed |
Humedics GmbH |
2015-09-30 |
| NCT01751399 |
A Single Dose Study of LY2605541 in Participants With Liver Impairment |
https://ClinicalTrials.gov/show/NCT01751399 |
Completed |
Eli Lilly and Company |
2013-09-30 |
| NCT01737684 |
A Single-Dose Study of the Pharmacokinetics of Vibegron (MK-4618) in Adults With Hepatic Insufficiency (MK-4618-013) |
https://ClinicalTrials.gov/show/NCT01737684 |
Completed |
Merck Sharp & Dohme Corp. |
2013-06-14 |
| NCT01687257 |
Sofosbuvir and Ribavirin in Patients With Chronic HCV With Cirrhosis and Portal Hypertension With or Without Liver Decompensation |
https://ClinicalTrials.gov/show/NCT01687257 |
Completed |
Gilead Sciences |
2015-01-31 |
| NCT01643447 |
Ulinastatin Preventing Postoperative Hepatic Failure in Hepatocellular Carcinoma (HCC) |
https://ClinicalTrials.gov/show/NCT01643447 |
Completed |
Eastern Hepatobiliary Surgery Hospital |
2014-12-31 |
| NCT01634230 |
Emergency Use of OCR-002 in Acute Liver Failure (ALF) |
https://ClinicalTrials.gov/show/NCT01634230 |
Completed |
Mallinckrodt |
2013-05-31 |
| NCT01548690 |
Safety Study of Ornithine Phenylacetate to Treat Patients With Acute Liver Failure/Severe Acute Liver Injury |
https://ClinicalTrials.gov/show/NCT01548690 |
Completed |
University of Texas Southwestern Medical Center |
2017-02-23 |
| NCT01512693 |
Assessment of Pharmacokinetics of Single Dose Odanacatib (MK-0822) in Participants With Moderate Hepatic Insufficiency (MK-0822-070) |
https://ClinicalTrials.gov/show/NCT01512693 |
Completed |
Merck Sharp & Dohme Corp. |
2012-04-24 |
| NCT01475136 |
A Study of LY2140023 in Hepatic Impaired Participants |
https://ClinicalTrials.gov/show/NCT01475136 |
Completed |
Eli Lilly and Company |
2012-12-31 |
| NCT01394497 |
Use of N-Acetylcysteine During Liver Procurement |
https://ClinicalTrials.gov/show/NCT01394497 |
Completed |
Azienda Ospedaliera di Padova |
2009-07-31 |
| NCT01390428 |
Study to Investigate the Influence of Hepatic Insufficiency on the Pharmacokinetics of Grazoprevir (MK-5172-013) |
https://ClinicalTrials.gov/show/NCT01390428 |
Completed |
Merck Sharp & Dohme Corp. |
2014-09-05 |
| NCT01383460 |
Efficacy of Granulocyte Colony-stimulating Factor and Erythropoetin for Patients With Acute-on-chronic Liver Failure |
https://ClinicalTrials.gov/show/NCT01383460 |
Completed |
Institute of Liver and Biliary Sciences, India |
2013-01-31 |
| NCT01366144 |
Veliparib, Paclitaxel, and Carboplatin in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery and Liver or Kidney Dysfunction |
https://ClinicalTrials.gov/show/NCT01366144 |
Active, not recruiting |
National Cancer Institute (NCI) |
2017-11-10 |
| NCT04351880 |
Meals MATTER: A Trial of Medically Tailored Meals 2 Weeks vs. 4 Weeks Post Hospital Discharge |
https://ClinicalTrials.gov/show/NCT04351880 |
Recruiting |
Kaiser Permanente |
2021-02-28 |
| NCT04347902 |
Lipid Emulsions and Liver Function - Results After 5 Years. |
https://ClinicalTrials.gov/show/NCT04347902 |
Completed |
Stanley Dudrick’s Memorial Hospital |
2020-03-31 |
| NCT04335058 |
Lactoferrin in Treatment of Fe Deficient Anemia In Cirrhosis |
https://ClinicalTrials.gov/show/NCT04335058 |
Recruiting |
Postgraduate Institute of Medical Education and Research |
2021-10-31 |
| NCT04243655 |
Use of HA 330-II for Hemofiltration in Patients With ALF as a Bridge to Liver Transplantation . |
https://ClinicalTrials.gov/show/NCT04243655 |
Recruiting |
Asian Institute of Gastroenterology, India |
2020-10-31 |
| NCT04238416 |
Intravenous Branched Chain Amino Acids for Hepatic Encephalopathy in ACLF |
https://ClinicalTrials.gov/show/NCT04238416 |
Recruiting |
Postgraduate Institute of Medical Education and Research |
2022-09-30 |
| NCT04237246 |
Comparative FK506 Drug Levels of Once Daily Advagraf in First Nations and Caucasian Patients With Liver Transplants |
https://ClinicalTrials.gov/show/NCT04237246 |
Completed |
University of Manitoba |
2019-11-27 |
| NCT04160039 |
Early Cycle Ergometry for Critically-Ill Liver Failure Patients in a Transplant Intensive Care Unit |
https://ClinicalTrials.gov/show/NCT04160039 |
Recruiting |
Medical College of Wisconsin |
2020-12-31 |
| NCT04157465 |
Anti-fungal Strategies in Acute-on-Chronic Liver Failure Patients |
https://ClinicalTrials.gov/show/NCT04157465 |
Recruiting |
Postgraduate Institute of Medical Education and Research |
2020-12-31 |
| NCT04147936 |
Study of the Safety and Tolerability of AXA1665 in Subjects With Mild and Moderate Hepatic Insufficiency |
https://ClinicalTrials.gov/show/NCT04147936 |
Recruiting |
Axcella Health, Inc |
2020-03-31 |
| NCT04143230 |
Identification of In-hospital Patients in Need of Palliative Care Using a New Simplified Screening Tool |
https://ClinicalTrials.gov/show/NCT04143230 |
Completed |
Azienda Ospedaliera Città della Salute e della Scienza di Torino |
2019-05-22 |
| NCT04139473 |
Randomized Trial of Hepaticojejunostomy Versus Duct-to-duct Anastomosis in Right Lobe Living Donor Liver Transplantation |
https://ClinicalTrials.gov/show/NCT04139473 |
Recruiting |
The University of Hong Kong |
2022-12-31 |
| NCT04122027 |
A Prospective Randomized Controlled Trial on the Use of Cerebral Oximetry in Adult Chinese Patients Undergoing Liver Transplantation |
https://ClinicalTrials.gov/show/NCT04122027 |
Recruiting |
The University of Hong Kong |
2020-05-31 |
| NCT04089969 |
Cardiac Risk Assessment Using Standard of Care Versus CTA and Heart Flow FFRct |
https://ClinicalTrials.gov/show/NCT04089969 |
Recruiting |
William Beaumont Hospitals |
2022-11-01 |
| NCT04013113 |
Efficacy and Safety of Hemoperfusion or Plasma Exchange Compared to Standard Medical Therapy in Patients With Acute on Chronic Liver Failure |
https://ClinicalTrials.gov/show/NCT04013113 |
Recruiting |
Institute of Liver and Biliary Sciences, India |
2020-07-31 |
| NCT03987893 |
PEG3350 in ACLF With Hepatic Encephalopathy |
https://ClinicalTrials.gov/show/NCT03987893 |
Recruiting |
Postgraduate Institute of Medical Education and Research |
2020-05-25 |
| NCT03920618 |
Three Types of Nucleotide/Nucleoside Analogues Treatment in HBV Related ACLF |
https://ClinicalTrials.gov/show/NCT03920618 |
Recruiting |
Third Affiliated Hospital, Sun Yat-Sen University |
2023-10-31 |
| NCT03882346 |
Study to Evaluate Safety and Efficacy of LifeLiver in Acute or Acute-on-Chronic Liver Failure Patients |
https://ClinicalTrials.gov/show/NCT03882346 |
Recruiting |
HLB Cell Co., Ltd. |
2022-03-31 |
| NCT03860155 |
Allogeneic ABCB5-positive Stem Cells for Treatment of Acute-on-Chronic Liver Failure |
https://ClinicalTrials.gov/show/NCT03860155 |
Recruiting |
RHEACELL GmbH & Co. KG |
2021-10-31 |
| NCT03842761 |
A Study to Test How Different Doses of BI 685509 Are Tolerated in Patients With Liver Problems |
https://ClinicalTrials.gov/show/NCT03842761 |
Recruiting |
Boehringer Ingelheim |
2021-05-21 |
| NCT03791190 |
RCA for CRRT in Liver Failure and High Risk Bleeding Patients |
https://ClinicalTrials.gov/show/NCT03791190 |
Recruiting |
Fourth Military Medical University |
2021-08-30 |
| NCT03754400 |
Efficacy of Albumin Therapy With Standard Medical Treatment (SMT) as Compared to Standard Medical Treatment (SMT) in Improving Patient Survival and Immune Modulation in Patients With Acute on Chronic Liver Failure (ASIA Trial). |
https://ClinicalTrials.gov/show/NCT03754400 |
Recruiting |
Institute of Liver and Biliary Sciences, India |
2020-07-30 |
| NCT03746392 |
Project to Improve Communication About Serious Illness - Pilot Study |
https://ClinicalTrials.gov/show/NCT03746392 |
Active, not recruiting |
University of Washington |
2020-06-30 |
| NCT03737448 |
TRimetazidine for acUte on Chronic Liver Failure STudy |
https://ClinicalTrials.gov/show/NCT03737448 |
Recruiting |
Martin Pharmaceuticals |
2020-02-28 |
| NCT03713489 |
Platelet Transfusion in HBV-related acute-on Chronic Liver Failure |
https://ClinicalTrials.gov/show/NCT03713489 |
Recruiting |
Nanfang Hospital of Southern Medical University |
2019-09-30 |
| NCT03702920 |
Short-term Survival of Subjects With Acute-on-chronic Liver Failure After Plasma Exchange With Human Serum Albumin 5% |
https://ClinicalTrials.gov/show/NCT03702920 |
Recruiting |
Grifols Therapeutics LLC |
2021-12-31 |
| NCT03668171 |
Mesenchymal Stem Cell Transplantation for Acute-on-chronic Liver Failure |
https://ClinicalTrials.gov/show/NCT03668171 |
Recruiting |
Xijing Hospital of Digestive Diseases |
2019-12-31 |
| NCT03667157 |
Liver Function After Intravenous Methylprednisolone Administration |
https://ClinicalTrials.gov/show/NCT03667157 |
Completed |
Medical University of Warsaw |
2016-10-30 |
| NCT03650920 |
Hepatitis C Virus (HCV) Positive Liver Grafts in HCV Negative Recipients |
https://ClinicalTrials.gov/show/NCT03650920 |
Enrolling by invitation |
Loma Linda University |
2021-09-30 |
| NCT03627013 |
Custodiol-N Solution Compared With Custodiol Solution in Organ Transplantation (Kidney, Liver and Pancreas) |
https://ClinicalTrials.gov/show/NCT03627013 |
Recruiting |
Dr. F. Köhler Chemie GmbH |
2023-05-01 |
| NCT03589820 |
Plasma Exchange and Continuous Hemodiafiltration in Treatment of Wilson’s Disease-related Liver Failure |
https://ClinicalTrials.gov/show/NCT03589820 |
Enrolling by invitation |
Third Affiliated Hospital, Sun Yat-Sen University |
2020-06-28 |
| NCT03577938 |
Study on the Optimal Strategy for Acute-on-chronic Liver Failure With Integrative Treatment |
https://ClinicalTrials.gov/show/NCT03577938 |
Recruiting |
Beijing 302 Hospital |
2020-12-30 |
| NCT03576859 |
Pyrophosphate Homeostasis and Hepatic Expression of ABCC6.Pyro-TH |
https://ClinicalTrials.gov/show/NCT03576859 |
Recruiting |
Centre Hospitalier Universitaire de Nice |
2020-11-06 |
| NCT03515980 |
An Investigational Study of Experimental Medication BMS-986231 Given in Participants With Different Levels of Liver Function |
https://ClinicalTrials.gov/show/NCT03515980 |
Completed |
Bristol-Myers Squibb |
2019-08-29 |
| NCT03465059 |
Safety and Pharmacokinetics of Zanubrutinib (BGB-3111) in Healthy Subjects and Those With Impaired Liver Function |
https://ClinicalTrials.gov/show/NCT03465059 |
Completed |
BeiGene |
2018-10-19 |
| NCT01261923 |
Pharmacokinetics of 9-cis-retinoic Acid (Alitretinoin, Toctino®) in Patients With Hepatic Disease |
https://ClinicalTrials.gov/show/NCT01261923 |
Completed |
University Hospital, Gentofte, Copenhagen |
2011-08-31 |
| NCT01254994 |
The Efficacy and Safety of Entecavir Treatment of Patients With Acute on Chronic Hepatitis B Liver Failure |
https://ClinicalTrials.gov/show/NCT01254994 |
Completed |
Sun Yat-sen University |
2009-07-31 |
| NCT01186588 |
A Study of Canagliflozin in Study Participants With Various Degrees of Impaired Hepatic (Liver) Function |
https://ClinicalTrials.gov/show/NCT01186588 |
Completed |
Johnson & Johnson Pharmaceutical Research & Development, L.L.C. |
2011-04-30 |
| NCT01160978 |
Donor Simvastatin Treatment in Organ Transplantation |
https://ClinicalTrials.gov/show/NCT01160978 |
Completed |
Helsinki University Central Hospital |
2016-08-01 |
| NCT01114490 |
Pharmacokinetics of Anacetrapib (MK0859) in Patients With Hepatic Insufficiency (MK-0859-039) |
https://ClinicalTrials.gov/show/NCT01114490 |
Completed |
Merck Sharp & Dohme Corp. |
2010-07-31 |
| NCT01074645 |
Randomized Controlled Trial of Tenofovir in Patients of Reactivation of Hepatitis B Presenting as Acute on Chronic Liver Failure |
https://ClinicalTrials.gov/show/NCT01074645 |
Completed |
Govind Ballabh Pant Hospital |
2009-06-30 |
| NCT01111318 |
Pharmacokinetics of Empagliflozin (BI 10773) in Patients With Impaired Liver Function |
https://ClinicalTrials.gov/show/NCT01111318 |
Completed |
Boehringer Ingelheim |
2010-11-30 |
| NCT01043926 |
Pharmacokinetics of Suvorexant in Participants With Hepatic Insufficiency (MK-4305-017) |
https://ClinicalTrials.gov/show/NCT01043926 |
Completed |
Merck Sharp & Dohme Corp. |
2010-04-14 |
| NCT01043887 |
Ridaforolimus in Patients With Hepatic Insufficiency (MK-8669-046) |
https://ClinicalTrials.gov/show/NCT01043887 |
Completed |
Merck Sharp & Dohme Corp. |
2010-04-30 |
| NCT01022476 |
Raltegravir in Patients With End Stage Liver Disease and in Transplant Recipients |
https://ClinicalTrials.gov/show/NCT01022476 |
Completed |
French National Institute for Health and Medical Research-French National Agency for Research on AIDS and Viral Hepatitis (Inserm-ANRS) |
2013-05-31 |
| NCT01019070 |
Hepatic Impaired Subjects Compared to Healthy Subjects Receiving Multi-dose BMS-650032 |
https://ClinicalTrials.gov/show/NCT01019070 |
Completed |
Bristol-Myers Squibb |
2011-08-31 |
| NCT01013194 |
Human Fetal Liver Cell Transplantation in Chronic Liver Failure |
https://ClinicalTrials.gov/show/NCT01013194 |
Completed |
The Mediterranean Institute for Transplantation and Advanced Specialized Therapies |
2011-04-30 |
| NCT01010906 |
A Study Investigating the Influence of Hepatic Insufficiency on the Pharmacokinetics of Vaniprevir (MK-7009-005) |
https://ClinicalTrials.gov/show/NCT01010906 |
Completed |
Merck Sharp & Dohme Corp. |
2010-06-11 |
| NCT00969813 |
A Safety and Tolerability Study of CP-690,550 in Subjects With Hepatic Impairment and Normal Hepatic Function |
https://ClinicalTrials.gov/show/NCT00969813 |
Completed |
Pfizer |
2010-01-31 |
| NCT00968591 |
Pharmacokinetics of Everolimus in Subjects With Hepatic Insufficiency |
https://ClinicalTrials.gov/show/NCT00968591 |
Completed |
Novartis |
2010-11-30 |
| NCT00950508 |
A Study of the Effect of Plasmaexchange in Patients With Acute Liver Failure |
https://ClinicalTrials.gov/show/NCT00950508 |
Completed |
Rigshospitalet, Denmark |
2009-07-31 |
| NCT00931060 |
Effects of Branched-Chain Amino Acids on Muscle Ammonia Metabolism in Patients With Cirrhosis and Healthy Subjects |
https://ClinicalTrials.gov/show/NCT00931060 |
Completed |
University of Aarhus |
2009-06-30 |
| NCT00886262 |
Study to Evaluate if the Drug Vasopressin Protects the Kidneys for Patients Undergoing Liver Transplant |
https://ClinicalTrials.gov/show/NCT00886262 |
Completed |
Medical University of South Carolina |
2011-08-31 |
| NCT00859053 |
Single-Dose Pharmacokinetics of BMS-790052 in Participants With Hepatic Impairment |
https://ClinicalTrials.gov/show/NCT00859053 |
Completed |
Bristol-Myers Squibb |
2009-09-30 |
| NCT04221672 |
The Effect of Terlipressin on Recovery of Liver Function After Hepatectomy |
https://ClinicalTrials.gov/show/NCT04221672 |
Recruiting |
Shanghai Zhongshan Hospital |
2020-12-30 |
| NCT03773887 |
Comparison of Inflammatory Profiles and Regenerative Potential in Alcoholic Liver Disease |
https://ClinicalTrials.gov/show/NCT03773887 |
Recruiting |
University Hospital, Lille |
2020-12-31 |
| NCT02910739 |
An Open-Label Study Investigating MK-8931 in Participants With Mild and Moderate Hepatic Insufficiency (MK-8931-016) |
https://ClinicalTrials.gov/show/NCT02910739 |
Completed |
Merck Sharp & Dohme Corp. |
2017-04-03 |
| NCT00831532 |
Study To Evaluate The Pharmacokinetics, Safety, And Tolerability Of Dimebon [Pf-01913539] In Subjects With Hepatic Impairment And Normal Hepatic Function |
https://ClinicalTrials.gov/show/NCT00831532 |
Completed |
Pfizer |
2009-08-31 |
| NCT02583698 |
Efficacy of Nonselective Beta Blocker vs Placebo in Patients With Acute-on-chronic Liver Failure With Small/ no Esophageal Varices |
https://ClinicalTrials.gov/show/NCT02583698 |
Completed |
Institute of Liver and Biliary Sciences, India |
2017-07-01 |
| NCT00805090 |
Open-Label, Single-Dose Study to Evaluate the Safety and PK of DIC075V in Subjects With Renal Insufficiency and Hepatic Impairment Compared to Healthy Subjects and Evaluate the Safety and Pharmacokinetics of HPβCD When Administered in DIC075V Compared to Sporanox® in Healthy Subjects |
https://ClinicalTrials.gov/show/NCT00805090 |
Completed |
Javelin Pharmaceuticals |
2009-03-31 |
| NCT03011424 |
Early Postoperative Extracorporal Liver Support Therapy (ELS) as a Tool to Manage Post Hepatectomy Liver Failure (PLF) |
https://ClinicalTrials.gov/show/NCT03011424 |
Completed |
Karolinska University Hospital |
2015-05-31 |
| NCT03968848 |
Investigate the Influence of Severe Hepatic Impairment on the Pharmacokinetics of Acalabrutinib and Its Metabolite |
https://ClinicalTrials.gov/show/NCT03968848 |
Completed |
Acerta Pharma BV |
2019-03-13 |
| NCT00781430 |
Study Evaluating The PK And Safety Of Neratinib In Healthy Subjects And Subjects With Chronic Liver Disease |
https://ClinicalTrials.gov/show/NCT00781430 |
Completed |
Puma Biotechnology, Inc. |
2010-02-28 |
| NCT00772148 |
Pharmacokinetics of LCP-Tacro™ Once Daily and Prograf® Twice A Day in Adult De Novo Liver Transplant Patients |
https://ClinicalTrials.gov/show/NCT00772148 |
Completed |
Veloxis Pharmaceuticals |
2010-05-31 |
| NCT00764049 |
Single Pass Albumin Dialysis in Patients With Cirrhosis |
https://ClinicalTrials.gov/show/NCT00764049 |
Completed |
Assistance Publique - Hôpitaux de Paris |
2012-01-31 |
| NCT00736541 |
N-acetylcysteine in Liver Transplantation |
https://ClinicalTrials.gov/show/NCT00736541 |
Completed |
University of Pittsburgh |
2007-04-30 |
| NCT00696826 |
A Study of MK0431 in Patients WIth Hepatic Insufficiency (0431-017)(COMPLETED) |
https://ClinicalTrials.gov/show/NCT00696826 |
Completed |
Merck Sharp & Dohme Corp. |
2004-05-31 |
| NCT00692341 |
Evaluation Of Hepatic Impairment On AG-013736 Pharmacokinetics |
https://ClinicalTrials.gov/show/NCT00692341 |
Completed |
Pfizer |
2008-10-31 |
| NCT00670124 |
Hypothermia to Prevent High Intracranial Pressure in Patients With Acute Liver Failure |
https://ClinicalTrials.gov/show/NCT00670124 |
Completed |
Rigshospitalet, Denmark |
2011-01-31 |
| NCT00655707 |
A Phase I/II Safety and Tolerability Dose Escalation Study of Autologous Stem Cells to Patients With Liver Insufficiency |
https://ClinicalTrials.gov/show/NCT00655707 |
Completed |
Imperial College London |
2009-04-30 |
| NCT00655304 |
The Effect of Prometheus (R) Liver Support Dialysis on Cerebral Metabolism in Acute Liver Failure |
https://ClinicalTrials.gov/show/NCT00655304 |
Completed |
Rigshospitalet, Denmark |
2010-12-31 |
| NCT00645021 |
Study Examining The Effect Of Hepatic Impairment On Safety, Toleration And How The Body Processes An Experimental Drug |
https://ClinicalTrials.gov/show/NCT00645021 |
Completed |
Pfizer |
2008-10-31 |
| NCT00614146 |
Recompensation of Exacerbated Liver Insufficiency With Hyperbilirubinemia and/or Encephalopathy and/or Renal Failure |
https://ClinicalTrials.gov/show/NCT00614146 |
Completed |
Baxter Healthcare Corporation |
2008-01-31 |
| NCT00608244 |
Pharmacokinetics of LCP-Tacro in Stable Liver Transplant Patients |
https://ClinicalTrials.gov/show/NCT00608244 |
Completed |
Veloxis Pharmaceuticals |
2008-06-30 |
| NCT01201720 |
Effects on Plasma Exchange on Functional Capacity of Serum Albumin, Circulatory Dysfunction, Renal and Cerebral Function in Cirrhotic Patients With “Acute-on-chronic Liver Failure” |
https://ClinicalTrials.gov/show/NCT01201720 |
Completed |
Grifols Therapeutics LLC |
2013-01-31 |
| NCT00522730 |
Safety and Tolerance on Lipids of Parenteral and Enteral Nutrition in Critically Ill Patients With Liver Failure |
https://ClinicalTrials.gov/show/NCT00522730 |
Completed |
Cliniques universitaires Saint-Luc- Université Catholique de Louvain |
2009-08-31 |
| NCT00509210 |
Study of Telaprevir in Subjects With Hepatic Impairment |
https://ClinicalTrials.gov/show/NCT00509210 |
Completed |
Vertex Pharmaceuticals Incorporated |
2008-06-30 |
| NCT00420134 |
Improvement of Liver Function in Liver Cirrhosis Patients After Autologous Mesenchymal Stem Cell Injection:a Phase I-II Clinical Trial |
https://ClinicalTrials.gov/show/NCT00420134 |
Completed |
Shahid Beheshti University of Medical Sciences |
2009-05-31 |
| NCT00416702 |
Safety and Pharmacokinetics of Indacaterol in Healthy Subjects and Those With Impaired Liver Function |
https://ClinicalTrials.gov/show/NCT00416702 |
Completed |
Novartis |
NA |
| NCT00407004 |
Elimination of Albumin-Bound Substances by MARS and Prometheus |
https://ClinicalTrials.gov/show/NCT00407004 |
Completed |
Medical University of Graz |
NA |
| NCT00325611 |
Multidisciplinary Inpatient Palliative Care Intervention |
https://ClinicalTrials.gov/show/NCT00325611 |
Completed |
Kaiser Permanente |
NA |
| NCT00314054 |
Study Evaluating the Safety of HCV-796 in Subjects With Liver Disease and in Healthy Adults |
https://ClinicalTrials.gov/show/NCT00314054 |
Completed |
Wyeth is now a wholly owned subsidiary of Pfizer |
2007-10-31 |
| NCT00287235 |
Efficacy of Albumin Dialysis to Treat Patients With Hepatic Encephalopathy Using The Molecular Adsorbent Recirculating System (MARS) |
https://ClinicalTrials.gov/show/NCT00287235 |
Completed |
Baxter Healthcare Corporation |
2003-11-30 |
| NCT00248625 |
N-acetylcysteine in Non-Acetaminophen Pediatric Acute Liver Failure |
https://ClinicalTrials.gov/show/NCT00248625 |
Completed |
University of Pittsburgh |
2009-09-30 |
| NCT00224705 |
The MARS® Albumin Dialysis System in Patients With Fulminant and Subfulminant Hepatic Failure |
https://ClinicalTrials.gov/show/NCT00224705 |
Completed |
Assistance Publique - Hôpitaux de Paris |
2009-01-31 |
| NCT00162552 |
Clinical Trial of Pentoxifylline in Patient With Cirrhosis |
https://ClinicalTrials.gov/show/NCT00162552 |
Completed |
Assistance Publique - Hôpitaux de Paris |
2007-12-31 |
| NCT00147043 |
Adult Stem Cell Therapy in Liver Insufficiency |
https://ClinicalTrials.gov/show/NCT00147043 |
Completed |
Imperial College London |
2005-06-30 |
| NCT00144248 |
A Pharmacokinetic Study to Assess Nevirapine [Viramune] Levels in HIV Infected Patients With Impaired Hepatic Functions |
https://ClinicalTrials.gov/show/NCT00144248 |
Completed |
Boehringer Ingelheim |
2006-06-30 |
| NCT00135694 |
Gradual Withdrawal of Immune System Suppressing Drugs in Patients Receiving a Liver Transplant |
https://ClinicalTrials.gov/show/NCT00135694 |
Completed |
National Institute of Allergy and Infectious Diseases (NIAID) |
2015-09-30 |
| NCT00030225 |
Phase 2 Evaluation of the ELAD System in the Management of Acute Liver Failure |
https://ClinicalTrials.gov/show/NCT00030225 |
Completed |
Vital Therapies, Inc. |
2003-02-28 |
| NCT00004467 |
Randomized Study of Acetylcysteine in Patients With Acute Liver Failure Not Caused by Acetaminophen |
https://ClinicalTrials.gov/show/NCT00004467 |
Completed |
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) |
2006-11-30 |