Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html


Study Counts

Type Study_count
Total_Studies 217
interventional 161
Observational 54
Registry 2

Studies over Time by Start Date

```

Interventional Trials

Intervention Type

intervention_type Study_Count
Drug 91
Device 13
Other 11
Drug|placebo 9
Procedure 8
Drug|Other 6
Biological 4
Behavioral 3
Biological|Other 3
Device|Drug 2
Device|Procedure 2
Biological|Device|Drug 1
Biological|Dietary Supplement|Drug|Other 1
Combination Product 1
Device|Drug|Procedure 1
Diagnostic Test 1
Dietary Supplement 1
Dietary Supplement|placebo 1
Drug|Other|Procedure 1
placebo|Procedure 1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country Study_Count
United States 47
NA 21
India 19
China 10
France 9
Germany 5
Italy 4
Austria 2
Belgium 2
Denmark 2
Germany|Hungary 2
Poland 2
Spain 2
Sweden 2
United Kingdom 2
Austria|Belgium|Denmark|France|Germany|Italy|Spain|Switzerland|United Kingdom 1
Austria|Belgium|Denmark|France|Germany|Romania|Spain|United Kingdom 1
Austria|Belgium|France|Germany|Spain 1
Belgium|France 1
Belgium|Netherlands|United Kingdom 1
Bulgaria 1
Canada 1
China|Hong Kong 1
Denmark|Finland|United Kingdom 1
Egypt 1
Finland 1
Germany|Romania 1
Germany|Russian Federation|Singapore 1
Hong Kong 1
Hungary|Poland 1
Iran, Islamic Republic of 1
Japan 1
Korea, Republic of 1
Romania 1
Russian Federation 1
Slovakia 1
United States|Australia|France|New Zealand|Spain 1
United States|Austria|Belgium|Denmark|France|Germany|Italy|Portugal|Spain|United Kingdom 1
United States|Belgium|Canada|Spain 1
United States|Belgium|Denmark 1
United States|Canada|United Kingdom 1
United States|Denmark|United Kingdom 1
United States|France|Spain 1
United States|United Kingdom 1
Vietnam 1

Sites per Study

Site_count Study_Count
1 103
2 21
3 8
4 7
5 1
6 1
7 1
8 4
9 1
10 1
11 4
12 1
15 1
17 1
19 1
20 1
21 1
24 1
25 1
32 1

Phase

Phase Study_Count
Phase 1 57
N/A 55
Phase 2 13
Phase 4 12
Phase 3 11
Phase 1/Phase 2 8
Phase 2/Phase 3 4
Early Phase 1 1

Number of Arms

Number_of_Arms Count_of_Studies
1 36
2 72
3 19
4 23
5 1
6 3
NA 7

Enrollment Metrics by Phase

Measure Early.Phase.1 N.A Phase.1 Phase.1.Phase.2 Phase.2 Phase.2.Phase.3 Phase.3 Phase.4
Min. 5 5.0000 15.00000 5.000 10.00000 40 55.0000 10.00000
1st Qu. 5 30.5000 24.00000 11.750 24.00000 67 125.0000 25.25000
Median 5 80.0000 29.00000 15.000 50.00000 80 157.0000 44.00000
Mean 5 136.3273 31.94643 16.375 73.07692 81 217.2727 42.16667
3rd Qu. 5 179.5000 35.00000 19.750 108.00000 94 263.0000 61.00000
Max. 5 660.0000 94.00000 30.000 275.00000 124 614.0000 68.00000

Trial Group Type

group_type Group_Count
Experimental 238
Active Comparator 72
No Intervention 16
Other 14
Placebo Comparator 12
NA 7

Intervention Model

intervention_model Study_Count
Parallel Assignment 116
Single Group Assignment 36
Crossover Assignment 6
Sequential Assignment 2
Factorial Assignment 1

Primary Purpose

primary_purpose Study_Count
Treatment 110
Basic Science 14
NA 11
Prevention 8
Other 7
Supportive Care 5
Diagnostic 4
Device Feasibility 1
Screening 1

Observational Studies

Studies by Country

Country Study_Count
China 13
United States 7
NA 5
Denmark 3
Germany 3
India 3
Belgium 2
Egypt 2
France 2
United Kingdom 2
Argentina 1
Canada 1
Finland 1
Norway 1
Spain|Austria|Belgium|Denmark|France|Germany|Hungary|Italy|Netherlands|Portugal|Slovakia|Switzerland|Turkey|United Kingdom 1
Sweden 1
Switzerland 1
Switzerland|United Kingdom 1
Taiwan 1
United States|Brazil|Canada|France|Germany|Greece|Italy|Sweden 1
United States|Canada 1
United States|Canada|United Kingdom 1

Sites per Study

Site_count Study_Count
1 43
2 1
3 1
4 2
11 1
12 2
14 1
20 1
45 1
48 1

Enrollment Metrics

Measure Observational
Min 10.000
1st Qu 63.000
Median 162.500
Mean 2758.278
3rd Qu 516.500
Max 113505.000

Observation Model

observational_model Study_Count
Cohort 36
Case-Only 8
Case-Control 3
Case Control 3
Other 3
NA 1

Time Perspective

time_perspective Study_Count
Prospective 40
Retrospective 9
NA 3
Cross-Sectional 2

Registries

Studies by Country

Country Study_Count
NA 1
Spain 1

Sites per Study

Site_count Study_Count
1 2

Enrollment Metrics

Measure Registries
Min 60
1st Qu 212
Median 364
Mean 364
3rd Qu 516
Max 668

Registry Model

observational_model Study_Count
Case-Only 1
Cohort 1

Time Perspective

time_perspective Study_Count
Prospective 1
NA 1

Follow-up

target_duration Study_Count
2 Years 2

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id brief_title link overall_status source primary_completion_date
NCT02375867 Steroids in Fulminant Hepatitis A in the Pediatric Age Group https://ClinicalTrials.gov/show/NCT02375867 Completed National Liver Institute, Egypt 2017-08-31
NCT03940742 A Study of Tirzepatide in Participants With Impaired Liver Function https://ClinicalTrials.gov/show/NCT03940742 Recruiting Eli Lilly and Company 2020-08-18
NCT03878329 Telemedicine Based Remote Home Monitoring After Liver Transplantation https://ClinicalTrials.gov/show/NCT03878329 Active, not recruiting University of Cincinnati 2019-07-01
NCT03341884 A Study of Ipatasertib in Participants With Mild, Moderate or Severe Hepatic Impairment Compared to Healthy Participants https://ClinicalTrials.gov/show/NCT03341884 Completed Genentech, Inc. 2018-06-26
NCT03312036 HEpatic Regeneration With COupled Plasma Filtration and Adsorption for Liver Extracorporeal Detoxification https://ClinicalTrials.gov/show/NCT03312036 Completed St. Orsola Hospital 2018-12-21
NCT03306667 Clinical Pharmacology of FYU-981 (Subjects With Hepatic Insufficiency) https://ClinicalTrials.gov/show/NCT03306667 Completed Mochida Pharmaceutical Company, Ltd. 2018-06-20
NCT03216668 TONKA Versus Legalon for Lowering Hepatic Enzymes in Liver Function Disorder Patients. https://ClinicalTrials.gov/show/NCT03216668 Recruiting Nhat Nhat Pharmaceutical Company 2019-06-30
NCT03172884 Study of Copanlisib in Hepatic or Renal Impairment https://ClinicalTrials.gov/show/NCT03172884 Completed Bayer 2020-03-13
NCT03082885 The Efficacy and Safety of Thymosin-α1 in Patients With HBV-related ACLF https://ClinicalTrials.gov/show/NCT03082885 Completed Sun Yat-sen University 2019-06-02
NCT03044639 Parenteral Lipid Emulsions and the Liver Function https://ClinicalTrials.gov/show/NCT03044639 Completed Stanley Dudrick’s Memorial Hospital 2016-10-31
NCT02946554 Phase II Safety Study of 2 Dose Regimens of HepaStem in Patients With ACLF https://ClinicalTrials.gov/show/NCT02946554 Active, not recruiting Promethera Biosciences 2019-07-31
NCT02894385 Effect of Hepatic and Renal Impairment on the Pharmacokinetics, Safety and Tolerability of BAY1841788 (ODM-201) https://ClinicalTrials.gov/show/NCT02894385 Completed Bayer 2017-04-10
NCT02837939 Transfer Factor Efficacy in the Management of Cirrhosis-associated Immune Dysfunction https://ClinicalTrials.gov/show/NCT02837939 Recruiting Pavol Jozef Safarik University 2020-07-31
NCT02753517 Hepato Biliary Scintigraphy to Assess the Risk of Postoperative Liver Failure Hepatectomies https://ClinicalTrials.gov/show/NCT02753517 Recruiting University Hospital, Lille 2020-11-30
NCT02719210 High Volume Plasma Exchange in Children With Acute Liver Failure and Acute on Chronic Liver Failure https://ClinicalTrials.gov/show/NCT02719210 Completed Institute of Liver and Biliary Sciences, India 2018-11-30
NCT02718079 High-Volume Plasma Exchange Versus Standard Medical Treatment in Patients With Acute Liver Failure https://ClinicalTrials.gov/show/NCT02718079 Completed Institute of Liver and Biliary Sciences, India 2018-10-08
NCT02691533 To Study the Immunomodulating Effects and Safety Profile of ω3 and ω6 PUFA Containing Intravenous Lipid Emulsion in Patients With Acute on Chronic Liver Failure https://ClinicalTrials.gov/show/NCT02691533 Completed Institute of Liver and Biliary Sciences, India 2017-12-31
NCT02689245 Randomized Controlled Trial Comparing the Efficacy and Safety of FMT in Hepatitis B Reactivation Leads to Acute on Chronic Liver Failure. https://ClinicalTrials.gov/show/NCT02689245 Completed Institute of Liver and Biliary Sciences, India 2018-03-13
NCT02687763 Safety and Efficacy of ProQuad® in Children 6-24 Month Being Evaluated for Solid Organ Transplant https://ClinicalTrials.gov/show/NCT02687763 Completed Medical University of South Carolina 2016-11-03
NCT02669680 Granulocyte Colony Stimulating Factor (G-CSF) to Treat Acute-on-chronic Liver Failure https://ClinicalTrials.gov/show/NCT02669680 Active, not recruiting University of Leipzig 2020-03-31
NCT02666352 A Study of the Pharmacokinetics of Uprifosbuvir (MK-3682) and Ruzasvir (MK-8408) in Participants With Moderate and Severe Hepatic Insufficiency (MK-3682-029) https://ClinicalTrials.gov/show/NCT02666352 Completed Merck Sharp & Dohme Corp. 2017-01-16
NCT02635347 Remote Ischemic Conditioning (RIC) in Recipients of Brain Death Donor Livers - A Feasibility and Safety Study https://ClinicalTrials.gov/show/NCT02635347 Completed Rutgers, The State University of New Jersey 2017-10-31
NCT02584283 Dual Hypothermic Oxygenated Perfusion of DCD Liver Grafts in Preventing Biliary Complications After Transplantation https://ClinicalTrials.gov/show/NCT02584283 Completed University Medical Center Groningen 2020-01-31
NCT03065699 Safety and Performance Trial of DIALIVE Liver Dialysis Device in Acute On Chronic Liver Failure Patients https://ClinicalTrials.gov/show/NCT03065699 Active, not recruiting Yaqrit Ltd 2019-12-31
NCT02573727 To Compare the Response Rate of Noradrenaline vs. Terlipressin in Hepatorenal Syndrome in Patients With Acute on Chronic Liver Failure https://ClinicalTrials.gov/show/NCT02573727 Completed Institute of Liver and Biliary Sciences, India 2017-01-31
NCT02786836 13C-Methacetin Breath Test for the Prediction of Outcome in in ALI or ALF https://ClinicalTrials.gov/show/NCT02786836 Completed University of Texas Southwestern Medical Center 2019-09-18
NCT02544113 A Randomized Controlled Clinical Trial of Thymoglobulin® After Liver Transplantation https://ClinicalTrials.gov/show/NCT02544113 Active, not recruiting The Cleveland Clinic 2020-09-30
NCT02467348 Incidence And Outcome Of Paracentesis Induced Circulatory Dysfunction In Acute-On-Chronic Liver Failure. https://ClinicalTrials.gov/show/NCT02467348 Completed Institute of Liver and Biliary Sciences, India 2017-01-31
NCT02460510 Role of Hypertonic Saline Versus Mannitol in the Management of Raised Intracranial Pressure in Patients With ALF https://ClinicalTrials.gov/show/NCT02460510 Completed Institute of Liver and Biliary Sciences, India 2015-11-30
NCT02457702 Mitochondrial Function in Patients With Severe Liver Disease https://ClinicalTrials.gov/show/NCT02457702 Recruiting University of Texas Southwestern Medical Center 2021-12-31
NCT02455115 Renal Perfusion, Filtration and Oxygenation After Liver Transplantation -Effects of av Postoperative Blood Pressure https://ClinicalTrials.gov/show/NCT02455115 Completed Sahlgrenska University Hospital, Sweden 2016-02-29
NCT02390713 Pneumatic Reversible Portal Vein Diameter Modulation After Major Hepatectomy https://ClinicalTrials.gov/show/NCT02390713 Recruiting Assistance Publique - Hôpitaux de Paris 2020-04-30
NCT02387814 A Study of Abemaciclib in Participants With Varying Degrees of Liver Impairment https://ClinicalTrials.gov/show/NCT02387814 Completed Eli Lilly and Company 2015-08-31
NCT02334800 A Study To Describe The Effect Of Impaired Hepatic Function Of The Pharmacokinetics Of Palbociclib https://ClinicalTrials.gov/show/NCT02334800 Completed Pfizer 2016-10-09
NCT02321371 Effect of Goal Directed Ammonia Lowering Therapy in Acute on Chronic Liver Failure Patients With Hepatic Encephalopathy. https://ClinicalTrials.gov/show/NCT02321371 Completed Institute of Liver and Biliary Sciences, India 2016-01-31
NCT02318836 Single-Dose Pharmacokinetics and Safety of Oral Lofexidine in Hepatically-Impaired Subjects https://ClinicalTrials.gov/show/NCT02318836 Completed US WorldMeds LLC 2014-10-31
NCT02310542 Comparison of Two Liver Dialysis Systems : MARS Versus SPAD in Severe Liver Failure https://ClinicalTrials.gov/show/NCT02310542 Completed Hospices Civils de Lyon 2017-09-30
NCT02265627 Pharmacokinetics, Safety and Tolerability of BIIL 284 BS in Patients With Hepatic Impairment in Comparison to Healthy Volunteers https://ClinicalTrials.gov/show/NCT02265627 Completed Boehringer Ingelheim 2000-09-30
NCT02259855 Pharmacokinetics (PK) of Tipranavir/Ritonavir, Ribavirin, Pegylated Interferon (Peg INF) in Hepatitis C (HCV) Subjects With Mild Hepatic Impairment and in HCV, Hepatitis B (HBV), Hepatitis D Infected Subjects or Alcoholic Cirrhosis With Moderate Hepatic Impairment https://ClinicalTrials.gov/show/NCT02259855 Completed Boehringer Ingelheim 2008-10-31
NCT02249442 Study to Determine the Pharmacokinetics on TPV/r in Subjects With Mild and Moderate Hepatic Insufficiency https://ClinicalTrials.gov/show/NCT02249442 Completed Boehringer Ingelheim 2004-06-30
NCT02191865 Nintedanib in Volunteers With Hepatic Impairment Compared With Healthy Volunteers https://ClinicalTrials.gov/show/NCT02191865 Completed Boehringer Ingelheim 2014-12-31
NCT02184091 Study to Evaluate the Effects of Underlying Renal or Hepatic Dysfunction on the Pharmacokinetics of Nevirapine https://ClinicalTrials.gov/show/NCT02184091 Completed Boehringer Ingelheim 1999-07-31
NCT02183376 Pharmacokinetics and Pharmacodynamics of BI 1356 in Subjects With Different Degrees of Liver Impairment as Compared to Healthy Subjects https://ClinicalTrials.gov/show/NCT02183376 Completed Boehringer Ingelheim 2009-03-31
NCT02170571 Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Dabigatran Etexilate in Patients With Moderate Hepatic Impairment Compared to Subjects With Normal Hepatic Function https://ClinicalTrials.gov/show/NCT02170571 Completed Boehringer Ingelheim 2005-12-31
NCT02161224 A Study to Investigate the Exposure and Safety and Tolerability of a Single Dose of FG-4592 in Subjects With Moderately Diminished Liver Function Compared to Those With Normal Liver Function https://ClinicalTrials.gov/show/NCT02161224 Completed Astellas Pharma Inc 2013-12-31
NCT02120547 Phase 1 Study of Multiple-Dose Pharmacokinetics of Cenicriviroc in Subjects With Mild and Moderate Hepatic Impairment https://ClinicalTrials.gov/show/NCT02120547 Completed Tobira Therapeutics, Inc. 2014-07-31
NCT02115321 Study of Efficacy and Safety of Grazoprevir (MK-5172) + Elbasvir (MK-8742) in Chronic Hepatitis C Participants With Child-Pugh (CP)-B Hepatic Insufficiency (MK-5172-059) https://ClinicalTrials.gov/show/NCT02115321 Completed Merck Sharp & Dohme Corp. 2015-03-05
NCT02090621 Extracorporeal Photopheresis After Liver Transplant https://ClinicalTrials.gov/show/NCT02090621 Completed Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia 2013-10-31
NCT02089659 A Study to Investigate the Influence of Hepatic Insufficiency on the Pharmacokinetics of Doravirine (MK-1439) (MK-1439-019) https://ClinicalTrials.gov/show/NCT02089659 Completed Merck Sharp & Dohme Corp. 2014-05-12
NCT01273493 A Pharmacokinetic Study of Trabectedin in Patients With Advanced Malignancies and Hepatic Dysfunction https://ClinicalTrials.gov/show/NCT01273493 Completed Janssen Research & Development, LLC 2014-04-30
NCT01968395 Pharmacokinetics of Caspofungin After One Dose in Patients With Liver Failure https://ClinicalTrials.gov/show/NCT01968395 Completed Erasme University Hospital 2014-08-31
NCT01946360 Role of 13C Methacetin Breath Test in Predicting Prognosis Among Patients With Acute or Acute on Chronic Liver Failure (ACLF). https://ClinicalTrials.gov/show/NCT01946360 Completed Institute of Liver and Biliary Sciences, India 2015-01-31
NCT01916993 Safety, Tolerability, and Pharmacokinetics of a Single Dose of NBI-98854 in Subjects With Mild,Moderate, or Severe Hepatic Insufficiency https://ClinicalTrials.gov/show/NCT01916993 Completed Neurocrine Biosciences 2013-12-31
NCT01870388 A Pharmacokinetic Study of Baricitinib in Participants With Liver Disease https://ClinicalTrials.gov/show/NCT01870388 Completed Eli Lilly and Company 2013-07-31
NCT01860326 Evaluate the Pharmacokinetics, Safety, and Tolerability of Alisporivir in Subjects With Hepatic Impairment Compared to Healthy Subjects https://ClinicalTrials.gov/show/NCT01860326 Completed Debiopharm International SA 2011-09-30
NCT01846455 Single Dose Pharmacokinetics of Suboxone Study in Hepatic Impaired Subjects https://ClinicalTrials.gov/show/NCT01846455 Completed Indivior Inc. 2013-04-30
NCT01836185 A Study of Evacetrapib (LY2484595) in Participants With Hepatic (Liver) Impairment https://ClinicalTrials.gov/show/NCT01836185 Completed Eli Lilly and Company 2013-10-31
NCT01797536 The Influence of Hepatic Insufficiency on the Pharmacokinetics of Elbasvir (MK-8742) (MK-8742-009) https://ClinicalTrials.gov/show/NCT01797536 Completed Merck Sharp & Dohme Corp. 2014-08-20
NCT01785082 Fast-track LiveR: Study for the Early Identification of Low-risk Patients After Partial Liver Resection by the LiMAx-test https://ClinicalTrials.gov/show/NCT01785082 Completed Humedics GmbH 2015-09-30
NCT01751399 A Single Dose Study of LY2605541 in Participants With Liver Impairment https://ClinicalTrials.gov/show/NCT01751399 Completed Eli Lilly and Company 2013-09-30
NCT01737684 A Single-Dose Study of the Pharmacokinetics of Vibegron (MK-4618) in Adults With Hepatic Insufficiency (MK-4618-013) https://ClinicalTrials.gov/show/NCT01737684 Completed Merck Sharp & Dohme Corp. 2013-06-14
NCT01687257 Sofosbuvir and Ribavirin in Patients With Chronic HCV With Cirrhosis and Portal Hypertension With or Without Liver Decompensation https://ClinicalTrials.gov/show/NCT01687257 Completed Gilead Sciences 2015-01-31
NCT01643447 Ulinastatin Preventing Postoperative Hepatic Failure in Hepatocellular Carcinoma (HCC) https://ClinicalTrials.gov/show/NCT01643447 Completed Eastern Hepatobiliary Surgery Hospital 2014-12-31
NCT01634230 Emergency Use of OCR-002 in Acute Liver Failure (ALF) https://ClinicalTrials.gov/show/NCT01634230 Completed Mallinckrodt 2013-05-31
NCT01548690 Safety Study of Ornithine Phenylacetate to Treat Patients With Acute Liver Failure/Severe Acute Liver Injury https://ClinicalTrials.gov/show/NCT01548690 Completed University of Texas Southwestern Medical Center 2017-02-23
NCT01512693 Assessment of Pharmacokinetics of Single Dose Odanacatib (MK-0822) in Participants With Moderate Hepatic Insufficiency (MK-0822-070) https://ClinicalTrials.gov/show/NCT01512693 Completed Merck Sharp & Dohme Corp. 2012-04-24
NCT01475136 A Study of LY2140023 in Hepatic Impaired Participants https://ClinicalTrials.gov/show/NCT01475136 Completed Eli Lilly and Company 2012-12-31
NCT01394497 Use of N-Acetylcysteine During Liver Procurement https://ClinicalTrials.gov/show/NCT01394497 Completed Azienda Ospedaliera di Padova 2009-07-31
NCT01390428 Study to Investigate the Influence of Hepatic Insufficiency on the Pharmacokinetics of Grazoprevir (MK-5172-013) https://ClinicalTrials.gov/show/NCT01390428 Completed Merck Sharp & Dohme Corp. 2014-09-05
NCT01383460 Efficacy of Granulocyte Colony-stimulating Factor and Erythropoetin for Patients With Acute-on-chronic Liver Failure https://ClinicalTrials.gov/show/NCT01383460 Completed Institute of Liver and Biliary Sciences, India 2013-01-31
NCT01366144 Veliparib, Paclitaxel, and Carboplatin in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery and Liver or Kidney Dysfunction https://ClinicalTrials.gov/show/NCT01366144 Active, not recruiting National Cancer Institute (NCI) 2017-11-10
NCT04351880 Meals MATTER: A Trial of Medically Tailored Meals 2 Weeks vs. 4 Weeks Post Hospital Discharge https://ClinicalTrials.gov/show/NCT04351880 Recruiting Kaiser Permanente 2021-02-28
NCT04347902 Lipid Emulsions and Liver Function - Results After 5 Years. https://ClinicalTrials.gov/show/NCT04347902 Completed Stanley Dudrick’s Memorial Hospital 2020-03-31
NCT04335058 Lactoferrin in Treatment of Fe Deficient Anemia In Cirrhosis https://ClinicalTrials.gov/show/NCT04335058 Recruiting Postgraduate Institute of Medical Education and Research 2021-10-31
NCT04243655 Use of HA 330-II for Hemofiltration in Patients With ALF as a Bridge to Liver Transplantation . https://ClinicalTrials.gov/show/NCT04243655 Recruiting Asian Institute of Gastroenterology, India 2020-10-31
NCT04238416 Intravenous Branched Chain Amino Acids for Hepatic Encephalopathy in ACLF https://ClinicalTrials.gov/show/NCT04238416 Recruiting Postgraduate Institute of Medical Education and Research 2022-09-30
NCT04237246 Comparative FK506 Drug Levels of Once Daily Advagraf in First Nations and Caucasian Patients With Liver Transplants https://ClinicalTrials.gov/show/NCT04237246 Completed University of Manitoba 2019-11-27
NCT04160039 Early Cycle Ergometry for Critically-Ill Liver Failure Patients in a Transplant Intensive Care Unit https://ClinicalTrials.gov/show/NCT04160039 Recruiting Medical College of Wisconsin 2020-12-31
NCT04157465 Anti-fungal Strategies in Acute-on-Chronic Liver Failure Patients https://ClinicalTrials.gov/show/NCT04157465 Recruiting Postgraduate Institute of Medical Education and Research 2020-12-31
NCT04147936 Study of the Safety and Tolerability of AXA1665 in Subjects With Mild and Moderate Hepatic Insufficiency https://ClinicalTrials.gov/show/NCT04147936 Recruiting Axcella Health, Inc 2020-03-31
NCT04143230 Identification of In-hospital Patients in Need of Palliative Care Using a New Simplified Screening Tool https://ClinicalTrials.gov/show/NCT04143230 Completed Azienda Ospedaliera Città della Salute e della Scienza di Torino 2019-05-22
NCT04139473 Randomized Trial of Hepaticojejunostomy Versus Duct-to-duct Anastomosis in Right Lobe Living Donor Liver Transplantation https://ClinicalTrials.gov/show/NCT04139473 Recruiting The University of Hong Kong 2022-12-31
NCT04122027 A Prospective Randomized Controlled Trial on the Use of Cerebral Oximetry in Adult Chinese Patients Undergoing Liver Transplantation https://ClinicalTrials.gov/show/NCT04122027 Recruiting The University of Hong Kong 2020-05-31
NCT04089969 Cardiac Risk Assessment Using Standard of Care Versus CTA and Heart Flow FFRct https://ClinicalTrials.gov/show/NCT04089969 Recruiting William Beaumont Hospitals 2022-11-01
NCT04013113 Efficacy and Safety of Hemoperfusion or Plasma Exchange Compared to Standard Medical Therapy in Patients With Acute on Chronic Liver Failure https://ClinicalTrials.gov/show/NCT04013113 Recruiting Institute of Liver and Biliary Sciences, India 2020-07-31
NCT03987893 PEG3350 in ACLF With Hepatic Encephalopathy https://ClinicalTrials.gov/show/NCT03987893 Recruiting Postgraduate Institute of Medical Education and Research 2020-05-25
NCT03920618 Three Types of Nucleotide/Nucleoside Analogues Treatment in HBV Related ACLF https://ClinicalTrials.gov/show/NCT03920618 Recruiting Third Affiliated Hospital, Sun Yat-Sen University 2023-10-31
NCT03882346 Study to Evaluate Safety and Efficacy of LifeLiver in Acute or Acute-on-Chronic Liver Failure Patients https://ClinicalTrials.gov/show/NCT03882346 Recruiting HLB Cell Co., Ltd. 2022-03-31
NCT03860155 Allogeneic ABCB5-positive Stem Cells for Treatment of Acute-on-Chronic Liver Failure https://ClinicalTrials.gov/show/NCT03860155 Recruiting RHEACELL GmbH & Co. KG 2021-10-31
NCT03842761 A Study to Test How Different Doses of BI 685509 Are Tolerated in Patients With Liver Problems https://ClinicalTrials.gov/show/NCT03842761 Recruiting Boehringer Ingelheim 2021-05-21
NCT03791190 RCA for CRRT in Liver Failure and High Risk Bleeding Patients https://ClinicalTrials.gov/show/NCT03791190 Recruiting Fourth Military Medical University 2021-08-30
NCT03754400 Efficacy of Albumin Therapy With Standard Medical Treatment (SMT) as Compared to Standard Medical Treatment (SMT) in Improving Patient Survival and Immune Modulation in Patients With Acute on Chronic Liver Failure (ASIA Trial). https://ClinicalTrials.gov/show/NCT03754400 Recruiting Institute of Liver and Biliary Sciences, India 2020-07-30
NCT03746392 Project to Improve Communication About Serious Illness - Pilot Study https://ClinicalTrials.gov/show/NCT03746392 Active, not recruiting University of Washington 2020-06-30
NCT03737448 TRimetazidine for acUte on Chronic Liver Failure STudy https://ClinicalTrials.gov/show/NCT03737448 Recruiting Martin Pharmaceuticals 2020-02-28
NCT03713489 Platelet Transfusion in HBV-related acute-on Chronic Liver Failure https://ClinicalTrials.gov/show/NCT03713489 Recruiting Nanfang Hospital of Southern Medical University 2019-09-30
NCT03702920 Short-term Survival of Subjects With Acute-on-chronic Liver Failure After Plasma Exchange With Human Serum Albumin 5% https://ClinicalTrials.gov/show/NCT03702920 Recruiting Grifols Therapeutics LLC 2021-12-31
NCT03668171 Mesenchymal Stem Cell Transplantation for Acute-on-chronic Liver Failure https://ClinicalTrials.gov/show/NCT03668171 Recruiting Xijing Hospital of Digestive Diseases 2019-12-31
NCT03667157 Liver Function After Intravenous Methylprednisolone Administration https://ClinicalTrials.gov/show/NCT03667157 Completed Medical University of Warsaw 2016-10-30
NCT03650920 Hepatitis C Virus (HCV) Positive Liver Grafts in HCV Negative Recipients https://ClinicalTrials.gov/show/NCT03650920 Enrolling by invitation Loma Linda University 2021-09-30
NCT03627013 Custodiol-N Solution Compared With Custodiol Solution in Organ Transplantation (Kidney, Liver and Pancreas) https://ClinicalTrials.gov/show/NCT03627013 Recruiting Dr. F. Köhler Chemie GmbH 2023-05-01
NCT03589820 Plasma Exchange and Continuous Hemodiafiltration in Treatment of Wilson’s Disease-related Liver Failure https://ClinicalTrials.gov/show/NCT03589820 Enrolling by invitation Third Affiliated Hospital, Sun Yat-Sen University 2020-06-28
NCT03577938 Study on the Optimal Strategy for Acute-on-chronic Liver Failure With Integrative Treatment https://ClinicalTrials.gov/show/NCT03577938 Recruiting Beijing 302 Hospital 2020-12-30
NCT03576859 Pyrophosphate Homeostasis and Hepatic Expression of ABCC6.Pyro-TH https://ClinicalTrials.gov/show/NCT03576859 Recruiting Centre Hospitalier Universitaire de Nice 2020-11-06
NCT03515980 An Investigational Study of Experimental Medication BMS-986231 Given in Participants With Different Levels of Liver Function https://ClinicalTrials.gov/show/NCT03515980 Completed Bristol-Myers Squibb 2019-08-29
NCT03465059 Safety and Pharmacokinetics of Zanubrutinib (BGB-3111) in Healthy Subjects and Those With Impaired Liver Function https://ClinicalTrials.gov/show/NCT03465059 Completed BeiGene 2018-10-19
NCT01261923 Pharmacokinetics of 9-cis-retinoic Acid (Alitretinoin, Toctino®) in Patients With Hepatic Disease https://ClinicalTrials.gov/show/NCT01261923 Completed University Hospital, Gentofte, Copenhagen 2011-08-31
NCT01254994 The Efficacy and Safety of Entecavir Treatment of Patients With Acute on Chronic Hepatitis B Liver Failure https://ClinicalTrials.gov/show/NCT01254994 Completed Sun Yat-sen University 2009-07-31
NCT01186588 A Study of Canagliflozin in Study Participants With Various Degrees of Impaired Hepatic (Liver) Function https://ClinicalTrials.gov/show/NCT01186588 Completed Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 2011-04-30
NCT01160978 Donor Simvastatin Treatment in Organ Transplantation https://ClinicalTrials.gov/show/NCT01160978 Completed Helsinki University Central Hospital 2016-08-01
NCT01114490 Pharmacokinetics of Anacetrapib (MK0859) in Patients With Hepatic Insufficiency (MK-0859-039) https://ClinicalTrials.gov/show/NCT01114490 Completed Merck Sharp & Dohme Corp. 2010-07-31
NCT01074645 Randomized Controlled Trial of Tenofovir in Patients of Reactivation of Hepatitis B Presenting as Acute on Chronic Liver Failure https://ClinicalTrials.gov/show/NCT01074645 Completed Govind Ballabh Pant Hospital 2009-06-30
NCT01111318 Pharmacokinetics of Empagliflozin (BI 10773) in Patients With Impaired Liver Function https://ClinicalTrials.gov/show/NCT01111318 Completed Boehringer Ingelheim 2010-11-30
NCT01043926 Pharmacokinetics of Suvorexant in Participants With Hepatic Insufficiency (MK-4305-017) https://ClinicalTrials.gov/show/NCT01043926 Completed Merck Sharp & Dohme Corp. 2010-04-14
NCT01043887 Ridaforolimus in Patients With Hepatic Insufficiency (MK-8669-046) https://ClinicalTrials.gov/show/NCT01043887 Completed Merck Sharp & Dohme Corp. 2010-04-30
NCT01022476 Raltegravir in Patients With End Stage Liver Disease and in Transplant Recipients https://ClinicalTrials.gov/show/NCT01022476 Completed French National Institute for Health and Medical Research-French National Agency for Research on AIDS and Viral Hepatitis (Inserm-ANRS) 2013-05-31
NCT01019070 Hepatic Impaired Subjects Compared to Healthy Subjects Receiving Multi-dose BMS-650032 https://ClinicalTrials.gov/show/NCT01019070 Completed Bristol-Myers Squibb 2011-08-31
NCT01013194 Human Fetal Liver Cell Transplantation in Chronic Liver Failure https://ClinicalTrials.gov/show/NCT01013194 Completed The Mediterranean Institute for Transplantation and Advanced Specialized Therapies 2011-04-30
NCT01010906 A Study Investigating the Influence of Hepatic Insufficiency on the Pharmacokinetics of Vaniprevir (MK-7009-005) https://ClinicalTrials.gov/show/NCT01010906 Completed Merck Sharp & Dohme Corp. 2010-06-11
NCT00969813 A Safety and Tolerability Study of CP-690,550 in Subjects With Hepatic Impairment and Normal Hepatic Function https://ClinicalTrials.gov/show/NCT00969813 Completed Pfizer 2010-01-31
NCT00968591 Pharmacokinetics of Everolimus in Subjects With Hepatic Insufficiency https://ClinicalTrials.gov/show/NCT00968591 Completed Novartis 2010-11-30
NCT00950508 A Study of the Effect of Plasmaexchange in Patients With Acute Liver Failure https://ClinicalTrials.gov/show/NCT00950508 Completed Rigshospitalet, Denmark 2009-07-31
NCT00931060 Effects of Branched-Chain Amino Acids on Muscle Ammonia Metabolism in Patients With Cirrhosis and Healthy Subjects https://ClinicalTrials.gov/show/NCT00931060 Completed University of Aarhus 2009-06-30
NCT00886262 Study to Evaluate if the Drug Vasopressin Protects the Kidneys for Patients Undergoing Liver Transplant https://ClinicalTrials.gov/show/NCT00886262 Completed Medical University of South Carolina 2011-08-31
NCT00859053 Single-Dose Pharmacokinetics of BMS-790052 in Participants With Hepatic Impairment https://ClinicalTrials.gov/show/NCT00859053 Completed Bristol-Myers Squibb 2009-09-30
NCT04221672 The Effect of Terlipressin on Recovery of Liver Function After Hepatectomy https://ClinicalTrials.gov/show/NCT04221672 Recruiting Shanghai Zhongshan Hospital 2020-12-30
NCT03773887 Comparison of Inflammatory Profiles and Regenerative Potential in Alcoholic Liver Disease https://ClinicalTrials.gov/show/NCT03773887 Recruiting University Hospital, Lille 2020-12-31
NCT02910739 An Open-Label Study Investigating MK-8931 in Participants With Mild and Moderate Hepatic Insufficiency (MK-8931-016) https://ClinicalTrials.gov/show/NCT02910739 Completed Merck Sharp & Dohme Corp. 2017-04-03
NCT00831532 Study To Evaluate The Pharmacokinetics, Safety, And Tolerability Of Dimebon [Pf-01913539] In Subjects With Hepatic Impairment And Normal Hepatic Function https://ClinicalTrials.gov/show/NCT00831532 Completed Pfizer 2009-08-31
NCT02583698 Efficacy of Nonselective Beta Blocker vs Placebo in Patients With Acute-on-chronic Liver Failure With Small/ no Esophageal Varices https://ClinicalTrials.gov/show/NCT02583698 Completed Institute of Liver and Biliary Sciences, India 2017-07-01
NCT00805090 Open-Label, Single-Dose Study to Evaluate the Safety and PK of DIC075V in Subjects With Renal Insufficiency and Hepatic Impairment Compared to Healthy Subjects and Evaluate the Safety and Pharmacokinetics of HPβCD When Administered in DIC075V Compared to Sporanox® in Healthy Subjects https://ClinicalTrials.gov/show/NCT00805090 Completed Javelin Pharmaceuticals 2009-03-31
NCT03011424 Early Postoperative Extracorporal Liver Support Therapy (ELS) as a Tool to Manage Post Hepatectomy Liver Failure (PLF) https://ClinicalTrials.gov/show/NCT03011424 Completed Karolinska University Hospital 2015-05-31
NCT03968848 Investigate the Influence of Severe Hepatic Impairment on the Pharmacokinetics of Acalabrutinib and Its Metabolite https://ClinicalTrials.gov/show/NCT03968848 Completed Acerta Pharma BV 2019-03-13
NCT00781430 Study Evaluating The PK And Safety Of Neratinib In Healthy Subjects And Subjects With Chronic Liver Disease https://ClinicalTrials.gov/show/NCT00781430 Completed Puma Biotechnology, Inc. 2010-02-28
NCT00772148 Pharmacokinetics of LCP-Tacro™ Once Daily and Prograf® Twice A Day in Adult De Novo Liver Transplant Patients https://ClinicalTrials.gov/show/NCT00772148 Completed Veloxis Pharmaceuticals 2010-05-31
NCT00764049 Single Pass Albumin Dialysis in Patients With Cirrhosis https://ClinicalTrials.gov/show/NCT00764049 Completed Assistance Publique - Hôpitaux de Paris 2012-01-31
NCT00736541 N-acetylcysteine in Liver Transplantation https://ClinicalTrials.gov/show/NCT00736541 Completed University of Pittsburgh 2007-04-30
NCT00696826 A Study of MK0431 in Patients WIth Hepatic Insufficiency (0431-017)(COMPLETED) https://ClinicalTrials.gov/show/NCT00696826 Completed Merck Sharp & Dohme Corp. 2004-05-31
NCT00692341 Evaluation Of Hepatic Impairment On AG-013736 Pharmacokinetics https://ClinicalTrials.gov/show/NCT00692341 Completed Pfizer 2008-10-31
NCT00670124 Hypothermia to Prevent High Intracranial Pressure in Patients With Acute Liver Failure https://ClinicalTrials.gov/show/NCT00670124 Completed Rigshospitalet, Denmark 2011-01-31
NCT00655707 A Phase I/II Safety and Tolerability Dose Escalation Study of Autologous Stem Cells to Patients With Liver Insufficiency https://ClinicalTrials.gov/show/NCT00655707 Completed Imperial College London 2009-04-30
NCT00655304 The Effect of Prometheus (R) Liver Support Dialysis on Cerebral Metabolism in Acute Liver Failure https://ClinicalTrials.gov/show/NCT00655304 Completed Rigshospitalet, Denmark 2010-12-31
NCT00645021 Study Examining The Effect Of Hepatic Impairment On Safety, Toleration And How The Body Processes An Experimental Drug https://ClinicalTrials.gov/show/NCT00645021 Completed Pfizer 2008-10-31
NCT00614146 Recompensation of Exacerbated Liver Insufficiency With Hyperbilirubinemia and/or Encephalopathy and/or Renal Failure https://ClinicalTrials.gov/show/NCT00614146 Completed Baxter Healthcare Corporation 2008-01-31
NCT00608244 Pharmacokinetics of LCP-Tacro in Stable Liver Transplant Patients https://ClinicalTrials.gov/show/NCT00608244 Completed Veloxis Pharmaceuticals 2008-06-30
NCT01201720 Effects on Plasma Exchange on Functional Capacity of Serum Albumin, Circulatory Dysfunction, Renal and Cerebral Function in Cirrhotic Patients With “Acute-on-chronic Liver Failure” https://ClinicalTrials.gov/show/NCT01201720 Completed Grifols Therapeutics LLC 2013-01-31
NCT00522730 Safety and Tolerance on Lipids of Parenteral and Enteral Nutrition in Critically Ill Patients With Liver Failure https://ClinicalTrials.gov/show/NCT00522730 Completed Cliniques universitaires Saint-Luc- Université Catholique de Louvain 2009-08-31
NCT00509210 Study of Telaprevir in Subjects With Hepatic Impairment https://ClinicalTrials.gov/show/NCT00509210 Completed Vertex Pharmaceuticals Incorporated 2008-06-30
NCT00420134 Improvement of Liver Function in Liver Cirrhosis Patients After Autologous Mesenchymal Stem Cell Injection:a Phase I-II Clinical Trial https://ClinicalTrials.gov/show/NCT00420134 Completed Shahid Beheshti University of Medical Sciences 2009-05-31
NCT00416702 Safety and Pharmacokinetics of Indacaterol in Healthy Subjects and Those With Impaired Liver Function https://ClinicalTrials.gov/show/NCT00416702 Completed Novartis NA
NCT00407004 Elimination of Albumin-Bound Substances by MARS and Prometheus https://ClinicalTrials.gov/show/NCT00407004 Completed Medical University of Graz NA
NCT00325611 Multidisciplinary Inpatient Palliative Care Intervention https://ClinicalTrials.gov/show/NCT00325611 Completed Kaiser Permanente NA
NCT00314054 Study Evaluating the Safety of HCV-796 in Subjects With Liver Disease and in Healthy Adults https://ClinicalTrials.gov/show/NCT00314054 Completed Wyeth is now a wholly owned subsidiary of Pfizer 2007-10-31
NCT00287235 Efficacy of Albumin Dialysis to Treat Patients With Hepatic Encephalopathy Using The Molecular Adsorbent Recirculating System (MARS) https://ClinicalTrials.gov/show/NCT00287235 Completed Baxter Healthcare Corporation 2003-11-30
NCT00248625 N-acetylcysteine in Non-Acetaminophen Pediatric Acute Liver Failure https://ClinicalTrials.gov/show/NCT00248625 Completed University of Pittsburgh 2009-09-30
NCT00224705 The MARS® Albumin Dialysis System in Patients With Fulminant and Subfulminant Hepatic Failure https://ClinicalTrials.gov/show/NCT00224705 Completed Assistance Publique - Hôpitaux de Paris 2009-01-31
NCT00162552 Clinical Trial of Pentoxifylline in Patient With Cirrhosis https://ClinicalTrials.gov/show/NCT00162552 Completed Assistance Publique - Hôpitaux de Paris 2007-12-31
NCT00147043 Adult Stem Cell Therapy in Liver Insufficiency https://ClinicalTrials.gov/show/NCT00147043 Completed Imperial College London 2005-06-30
NCT00144248 A Pharmacokinetic Study to Assess Nevirapine [Viramune] Levels in HIV Infected Patients With Impaired Hepatic Functions https://ClinicalTrials.gov/show/NCT00144248 Completed Boehringer Ingelheim 2006-06-30
NCT00135694 Gradual Withdrawal of Immune System Suppressing Drugs in Patients Receiving a Liver Transplant https://ClinicalTrials.gov/show/NCT00135694 Completed National Institute of Allergy and Infectious Diseases (NIAID) 2015-09-30
NCT00030225 Phase 2 Evaluation of the ELAD System in the Management of Acute Liver Failure https://ClinicalTrials.gov/show/NCT00030225 Completed Vital Therapies, Inc. 2003-02-28
NCT00004467 Randomized Study of Acetylcysteine in Patients With Acute Liver Failure Not Caused by Acetaminophen https://ClinicalTrials.gov/show/NCT00004467 Completed National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 2006-11-30

Observational Studiess

#If less then 500 studies

nct_id brief_title link overall_status source primary_completion_date
NCT03281278 A Prospective Study of Application of Platelet Mapping in HBV-related Acute-on-chronic-liver Failure in China https://ClinicalTrials.gov/show/NCT03281278 Completed Nanfang Hospital of Southern Medical University 2018-08-13
NCT03281265 A Retrospective Multicenter Study of HBV-related Pre-acute-on-chronic Liver Failure in China https://ClinicalTrials.gov/show/NCT03281265 Completed Nanfang Hospital of Southern Medical University 2017-02-28
NCT03270774 Central Venous Catheter Colonisation Among Critically Ill Patients in Intensive Care Units https://ClinicalTrials.gov/show/NCT03270774 Completed Makerere University 2017-04-10
NCT03184636 Acute-On-Chronic Liver Failure in Zagazig University Hospitals https://ClinicalTrials.gov/show/NCT03184636 Completed Zagazig University 2018-08-11
NCT03056612 Predicting Acute-on-Chronic Liver Failure in Cirrhosis (PREDICT) Study https://ClinicalTrials.gov/show/NCT03056612 Completed European Foundation for Study of Chronic Liver Failure 2018-07-31
NCT02965560 Exploring Biomarkers Predicting the Outcome of Acute-on-chronic Liver Failure https://ClinicalTrials.gov/show/NCT02965560 Completed First Affiliated Hospital of Zhejiang University 2017-10-10
NCT02846441 Interstage Assessment of Remnant Liver Function in ALPPS https://ClinicalTrials.gov/show/NCT02846441 Completed Hospital Italiano de Buenos Aires 2016-03-31
NCT02818218 SVC and Its Relationship to CVP Measurements in Liver Transplantation https://ClinicalTrials.gov/show/NCT02818218 Recruiting The Cleveland Clinic 2021-12-31
NCT02557724 Mobilization of Mesenchymal Stem Cells During Liver Transplantation https://ClinicalTrials.gov/show/NCT02557724 Completed Rutgers, The State University of New Jersey 2017-07-31
NCT02457637 Chinese CLIF-C Acute-on-Chronic Liver Disease and Liver Failure Study https://ClinicalTrials.gov/show/NCT02457637 Completed Shanghai Jiao Tong University School of Medicine 2016-12-31
NCT02307890 The Relationship of Initial Liver Profile and Outcome After Transplantation https://ClinicalTrials.gov/show/NCT02307890 Recruiting University of Edinburgh 2019-08-31
NCT02307409 Assessment of Coagulation Profile and Haematopoietic Responses in Patients With Acute-on-chronic Liver Failure During Systemic Inflammatory Response (SIRS) and Sepsis https://ClinicalTrials.gov/show/NCT02307409 Completed Institute of Liver and Biliary Sciences, India 2016-04-01
NCT01276275 Extended Drug Utilization Study Among Patients Exposed to Ticagrelor, Clopidogrel and Prasugrel https://ClinicalTrials.gov/show/NCT01276275 Completed AstraZeneca 2015-04-30
NCT02041637 Unknown Cause of Acute Liver Failure https://ClinicalTrials.gov/show/NCT02041637 Completed Assistance Publique - Hôpitaux de Paris 2016-12-31
NCT01922323 Metabolomics of Liver Regeneration Following Partial Hepatectomy in Healthy Living Liver Donors https://ClinicalTrials.gov/show/NCT01922323 Completed Baylor Research Institute 2016-09-26
NCT01891526 Single Dose of 9-cis-retinoic Acid in Hepatic Patients https://ClinicalTrials.gov/show/NCT01891526 Completed University Hospital, Gentofte, Copenhagen 2012-06-30
NCT01878305 Neuromonitoring of Hepatic Encephalopathy https://ClinicalTrials.gov/show/NCT01878305 Completed University of Helsinki 2011-12-31
NCT01872767 Spectrum, Profile and Outcome of Infections in Patients With Cirrhosis and/ or Acute on Chronic Liver Failure https://ClinicalTrials.gov/show/NCT01872767 Completed Institute of Liver and Biliary Sciences, India 2014-11-30
NCT01826760 Study of the Model to Predict 3-month Mortality Risk of Acute-on-chronic Hepatitis B Liver Failure https://ClinicalTrials.gov/show/NCT01826760 Completed Wenzhou Medical University 2010-05-31
NCT01597102 Cerebrovascular Autoregulation During and After Liver Transplantation https://ClinicalTrials.gov/show/NCT01597102 Recruiting Johannes Gutenberg University Mainz 2020-12-31
NCT01425385 Autoregulation Assessment During Liver Transplantation https://ClinicalTrials.gov/show/NCT01425385 Completed Johns Hopkins University 2012-09-30
NCT01404793 SPME For Metabolomics And Concomitant Measurements Of Rocuronium Bromide Levels In Liver Transplantation https://ClinicalTrials.gov/show/NCT01404793 Completed University Health Network, Toronto 2014-04-30
NCT04332484 Global Coagulation Assessment in Cirrhosis and ACLF https://ClinicalTrials.gov/show/NCT04332484 Completed Postgraduate Institute of Medical Education and Research 2019-08-31
NCT04310787 Long-term Prognosis of Patients With Hepatitis B Related Acute-on-chronic Liver Failure https://ClinicalTrials.gov/show/NCT04310787 Recruiting Third Affiliated Hospital, Sun Yat-Sen University 2020-08-15
NCT04170309 Collection of Data of Ceftobiprole Treated Patients: Comparison of Patients With and Without Certain Diseases https://ClinicalTrials.gov/show/NCT04170309 Recruiting Correvio International Sarl 2021-12-31
NCT04119973 A Multicenter Prospective Study of Application of Platelet Mapping in Acute-on-chronic-liver Failure in China https://ClinicalTrials.gov/show/NCT04119973 Completed Nanfang Hospital of Southern Medical University 2019-08-04
NCT04116242 MERTK Signalling in Monocytes/Macrophages in Patients With Liver Disease https://ClinicalTrials.gov/show/NCT04116242 Recruiting University Hospital, Basel, Switzerland 2020-08-31
NCT04097704 Pharmacogenetics Sampling of the CC-90007-CP-003 Study Cohort https://ClinicalTrials.gov/show/NCT04097704 Completed Celgene 2019-11-01
NCT04058327 A Study of MHE in Patients With Liver Diseases https://ClinicalTrials.gov/show/NCT04058327 Recruiting Tongji Hospital 2020-06-30
NCT04054037 A Study of AARC Standards on Diagnosis and Treatment of Patients With HBV-ACLF in China (AARC China Study) https://ClinicalTrials.gov/show/NCT04054037 Recruiting Tongji Hospital 2022-04-01
NCT03992898 Nomogram Analysis for HBV Related Acute-on-chronic Liver Failure https://ClinicalTrials.gov/show/NCT03992898 Completed Sun Yat-sen University 2019-10-01
NCT03977857 Computed Tomography Liver Volume for Predicting Short-term Mortality in Hepatitis B‐Acute‐on‐Chronic Liver Failure https://ClinicalTrials.gov/show/NCT03977857 Completed First Affiliated Hospital Xi’an Jiaotong University 2019-12-31
NCT03864497 Myocardial Perfusion Imaging in Liver Transplantation Candidates https://ClinicalTrials.gov/show/NCT03864497 Completed University Hospital Birmingham NHS Foundation Trust 2019-06-30
NCT03833297 Monitoring the HePAtological TOXicity of Drugs (HePATOX) https://ClinicalTrials.gov/show/NCT03833297 Recruiting Groupe Hospitalier Pitie-Salpetriere 2020-02-04
NCT03723317 Associated Balance of Risk Score - Comprehensive Complication Index for the Prediction of Post-transplant Survival https://ClinicalTrials.gov/show/NCT03723317 Completed European Hepatocellular Cancer Liver Transplant Group 2018-10-15
NCT03641872 A Validation Cohort for ACLF Diagnosis and Prognosis https://ClinicalTrials.gov/show/NCT03641872 Active, not recruiting Shanghai Jiao Tong University School of Medicine 2020-04-21
NCT03640728 The Efficacy and Safety of Nucleos(t)Ide Analogues in the Treatment of HBV-related Acute-on-chronic Liver Failure https://ClinicalTrials.gov/show/NCT03640728 Recruiting First Affiliated Hospital Xi’an Jiaotong University 2021-04-30
NCT03598465 Evaluating the Association Between Sphingolipid Metabolites and Post-hepatectomy Liver Failure https://ClinicalTrials.gov/show/NCT03598465 Recruiting Nanfang Hospital of Southern Medical University 2021-10-01
NCT03509194 Better Diagnostic Tools for Children and Adolescents With Acute Liver Failure and Chronic Liver Insufficiency https://ClinicalTrials.gov/show/NCT03509194 Recruiting Rigshospitalet, Denmark 2020-12-17
NCT03456518 Pattern of Acute on Chronic Liver Failure in Patient With HCV Related Chronic Liver Disease https://ClinicalTrials.gov/show/NCT03456518 Completed Assiut University 2019-10-31
NCT01086293 Risk of Acute Liver Failure Among Patients With Type 2 Diabetes Exposed to Oral Antidiabetic Treatments https://ClinicalTrials.gov/show/NCT01086293 Completed AstraZeneca 2015-12-31
NCT01081197 Somatic Disease Among Alcohol Abusers in an Out-day Patients’ Clinic https://ClinicalTrials.gov/show/NCT01081197 Completed Levanger Hospital 2012-12-31
NCT00986648 A Multi-Center Group to Study Acute Liver Failure in Children https://ClinicalTrials.gov/show/NCT00986648 Completed University of Pittsburgh 2015-12-31
NCT00956891 Therapeutic Effects of Liver Failure Patients Caused by Chronic Hepatitis B After Autologous MSCs Transplantation https://ClinicalTrials.gov/show/NCT00956891 Completed Sun Yat-sen University 2009-06-30
NCT00929032 Liver Transplantation and Reticuloendothelial Clearance Capacity https://ClinicalTrials.gov/show/NCT00929032 Completed University of Edinburgh 2010-07-31
NCT00827723 Indocyanine Green and Portal Pressure in Viral and Alcoholic Cirrhotic Patients With Hepatocarcinoma https://ClinicalTrials.gov/show/NCT00827723 Completed University of Lausanne Hospitals 2018-02-28
NCT00823758 Understanding Patient’s Knowledge and Use of Acetaminophen https://ClinicalTrials.gov/show/NCT00823758 Active, not recruiting M.D. Anderson Cancer Center 2020-12-01
NCT00808691 Microcirculation and Oxidative Stress in Critical Ill Patients in Surgical Intensive Care Unit https://ClinicalTrials.gov/show/NCT00808691 Completed National Taiwan University Hospital 2010-07-31
NCT00518440 A Multi-Center Trial to Study Acute Liver Failure in Adults https://ClinicalTrials.gov/show/NCT00518440 Active, not recruiting University of Texas Southwestern Medical Center 2020-08-31
NCT00488917 Sepsis, Endothelial Function, and Lipids in Critically Ill Patients With Liver Failure (the SELLIFA Study) https://ClinicalTrials.gov/show/NCT00488917 Completed Cliniques universitaires Saint-Luc- Université Catholique de Louvain 2009-08-31
NCT00341705 The Second Multicenter Hemophilia Cohort Study https://ClinicalTrials.gov/show/NCT00341705 Completed National Institutes of Health Clinical Center (CC) NA
NCT00245310 Indocyangreen Elimination in Cirrhosis and Acute Liver Failure https://ClinicalTrials.gov/show/NCT00245310 Completed Heidelberg University 2010-10-31
NCT00836420 Cerebral Microdialysis in Patients With Fulminant Hepatic Failure https://ClinicalTrials.gov/show/NCT00836420 Completed Rigshospitalet, Denmark 2015-10-31
NCT00059267 Prevention of Recurrent Hepatitis B After Liver Transplantation https://ClinicalTrials.gov/show/NCT00059267 Completed National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 2007-11-30

Registries

#If less then 500 registries

nct_id brief_title link overall_status source primary_completion_date
NCT02813538 Major Liver Resection: Early Clotting Disorders and Functional Impairment. https://ClinicalTrials.gov/show/NCT02813538 Completed Hospital General Universitario Gregorio Marañon 2018-10-31
NCT02800421 Prognostic Impact of Organ Damage in STEMI Patients https://ClinicalTrials.gov/show/NCT02800421 Completed Inha University Hospital 2014-12-31